Esthesioneuroblastoma is an infrequent malignant skull base tumor located in the anterior skull base that originates in the olfactory neuroepithelial cells. Its origin is extracranial and extends through the lamina cribrosa to the endocranium. It is characterized by local aggressiveness and it first spreads to the cervical lymph nodes.
Clinically it is accompanied by sinusitis, facial pain, nasal obstruction, alterations in the sense of smell, bleeding, ocular proptosis, etc.
The ideal treatment is total resection with tumor-free margins, followed by an evaluation of the possibiltiy of radiation therapy. It is considered to generally have a better prognosis than other kinds of tumors which can occur in nasal passages.
Our team prioritizes endoscopic endonasal treatment for extracranial and intracranial tumors when it is possible to completely remove the tumor. Otherwise a cranio-endoscopic approach is performed to meet the objective of treating the cancer effectively.